Intuition
Every symmetric matrix can be diagonalised, and better than that, by a rotation or reflection of the axes: it has an orthonormal basis of eigenvectors. In that basis it does nothing but stretch each axis by its eigenvalue. Conversely, only symmetric matrices can be described that way.
A well-made spring mattress, pressed anywhere, pushes back along a few perpendicular directions, each with its own stiffness. Knowing those directions and stiffnesses is knowing the mattress completely.
Orthogonal diagonalisation
A matrix is orthogonally diagonalisable when with orthogonal and diagonal: the columns of are an orthonormal basis of eigenvectors and the diagonal of holds their eigenvalues, in the same order. Since this is a diagonalisation. The spectral theorem says exactly which real matrices allow it: the symmetric ones.